Diisopropylamine → HCID 20213089, compound

Participants

Reaction Steps

0.1 Mol of 3-cyano-3,3-diphenyl-2-methylpropionyl chloride were added dropwise while cooling and stirring to 50 g (0.5 mol) of diisopropylamine. The mixture was left standing at room temperature overnight and heated at 40°-50° C. for 30 minutes. The mixture was poured into water and isolated as described above for the preparation of 3-cyano-3,3-diphenyl-2-ethyl-N,N-dimethyl-propanamide. The amide was crystallized from a mixture of toluen and ether. Yield: 25 g (50%), melting at 195°-205° C.

Provenance & Evidence