Aluminum(III) Chloride → HCID 57160591, compound

HRID 1906310Notes

Reaction equation

HRID 1906310 reaction equation
[C:1]([C:3]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[CH:4]([CH3:14])[C:5]([N:7]([CH:11]([CH3:13])[CH3:12])[CH:8]([CH3:10])[CH3:9])=O)#[N:2].[H-].[H-].[H-].[H-].[Li+].[Al+3].[Al+3].[Cl-].[Cl-].[Cl-]>>[CH:11]([N:7]([CH:8]([CH3:10])[CH3:9])[CH2:5][CH:4]([CH3:14])[C:3]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH2:1][NH2:2])([CH3:12])[CH3:13]

Participants

4

Reactant 3

HCID 6451240Aluminum(III) ChlorideHCID 20213089HCID 20213089, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 57160591HCID 57160591, compound

Procedure

This compound was prepared from 3-cyano-3,3-diphenyl-2-methyl-N,N-diisopropyl-propanamide, essentially as described in Example 6, but per mole of starting material are used 3 moles of LiAlH4 and 3 moles of AlCl3, and the amide is added slowly to the reducing agent under reflux and while stirring, whereupon the mixture was refluxed for 8-16 hours.

Workup

  1. temperatureunder reflux
  2. temperaturewas refluxed for 8-16 hours

Sources & evidence

ORD record
ord-7fe4c0c141954a628bdfd1ee8c0894eb
Source dataset
uspto-grants-1987_03
Patent number
US04650900

Reaction notes

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