O-ethylhydroxylamine hydrochloride → HCID 135974007, compound

HRID 1906352Notes

Reaction equation

HRID 1906352 reaction equation
[OH:1][C:2]1[CH2:7][CH:6]([C:8]2[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[C:10]([C:16](=[S:23])[NH:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:9]=2[CH3:24])[CH2:5][C:4](=[O:25])[C:3]=1[C:26](=O)[CH2:27][CH3:28].Cl.[CH2:31]([O:33][NH2:34])[CH3:32]>>[CH2:31]([O:33][N:34]=[C:26]([C:3]1[C:4](=[O:25])[CH2:5][CH:6]([C:8]2[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[C:10]([C:16](=[S:23])[NH:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:9]=2[CH3:24])[CH2:7][C:2]=1[OH:1])[CH2:27][CH3:28])[CH3:32]

Participants

3

Reactant 2

HCID 76850O-ethylhydroxylamine hydrochlorideHCID 178473558HCID 178473558, compound

Product 1

HCID 135974007HCID 135974007, compound

Procedure

Reaction of 3-hydroxy-5-(3-ethoxycarbonylthiocarbamoyl-2,4,6-trimethylphenyl)-2-propionylcyclohex-2-en-1-one with ethoxyamine hydrochloride following essentially the same procedure as that described in Example 1 part (v) gave 2-[1-(ethoxyimino)propyl]-3-hydroxy-5-(3-ethoxycarbonylthiocarbamoyl-2,4,6-trimethylphenyl)cyclohex-2-en-1-one (23) as a yellow oil. the compound was characterized by its proton nuclear magnetic resonance spectrum and the data are recorded in Table 3, Example 11.

Sources & evidence

ORD record
ord-96bc3153a76041d69436fd43b546846f
Source dataset
uspto-grants-1987_03
Patent number
US04652303

Reaction notes

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