Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(o-Tolyl)piperazine hydrochloride → 2-Carbamoyl-7-{2-hydroxy-3-[4-(2-methylphenyl)piperazinyl]propoxy}benzofuran
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(o-Tolyl)piperazine hydrochloride | HCID 12227895 | — |
| 반응물 | 2-Carbamoyl-7-(2,3-epoxypropoxy)benzofuran | HCID 13729403 | — |
| 생성물 | 2-Carbamoyl-7-{2-hydroxy-3-[4-(2-methylphenyl)piperazinyl]propoxy}benzofuran | HCID 13729385 | — |
반응 단계
The procedures of Example 10 were repeated except that 1.2 g (0.005 mole) of 2-carbamoyl-7-(2,3-epoxypropoxy)benzofuran and 1.2 g (0.0055 mole) of 1-(2-methylphenyl)piperazine hydrochloride were employed. The obtained concentrated residue was crystallized from ethyl acetate and petroleum ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04652566 |
| 출처 데이터셋 | uspto-grants-1987_03 |
| ORD ID | ord-c920629ff2c34bcbb35aacb3fe1b01e1 |
| 출처 메모 | uspto-grants-1987_03 |