4-Propanoylanisole → HCID 20210193, compound

Participants

Reaction Steps

A mixture of 100 g of p-methoxypropiophenone, 250 ml of methanol and 5 g of a 5% strength ruthenium/active carbon catalyst was hydrogenated at 120° C. and under 150 bar until absorption of hydrogen was virtually complete. The catalyst was removed, the solvent was distilled off under 1013 mbar and the residue was then fractionated. 92 g of a colorless liquid having a boiling point of 73°-75° C. 0.01 mbar and a fine woody note were obtained.

Provenance & Evidence