Hydrochloric Acid → HCID 13386126, compound

Participants

Reaction Conditions

Reaction Steps

To 500 mg of the compound prepared in Example 6 were added 20 ml of 2N sodium hydroxide solution, and the mixture was heated for 1 hour in a water bath at 90° C. The reaction mixture was neutrallized with 2N hydrochloric acid to be acidic condition (pH 3) under cooling in an ice bath. The resulting precipitates were collected by filtration and recrystallized from a mixture of benzene and hexane to give 374 mg (83.9%) of the desired product as colorless powder, mp 118°-119° C.

Provenance & Evidence