Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1906741Generated: October 31, 2026

2-Fluorobenzylamine → N-[(2-Fluorophenyl)methyl]-3-methyl-3H-imidazo[4,5-c]pyridin-4-amine

https://huagongshe.com/reaction/1906741

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzylamineHCID 66649—
Reactant4-Chloro-3-methyl-3H-imidazo[4,5-c]pyridineHCID 20210746—
ProductN-[(2-Fluorophenyl)methyl]-3-methyl-3H-imidazo[4,5-c]pyridin-4-amineHCID 13264455—

Reaction Steps

A mixture of 16.76 g of 4-chloro-3-methyl-3H-imidazo(4,5-c)pyridine and 30 g of o-fluorobenzylamine is melted at 180° for 2 hours. After customary working up, 4-o-fluorobenzylamino-3-methyl-3H-imidazo-(4,5-c)pyridine of m.p. 163°-164° is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04654350
Source datasetuspto-grants-1987_03
ORD IDord-271e549f45f94e2eaa21031df034a36f
Source noteuspto-grants-1987_03