1-Chloro-4-(chloromethyl)benzene → HCID 13800177, compound

HRID 1906939Notes

Reaction equation

HRID 1906939 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Cl)=[CH:4][CH:3]=1.[Cl:10][C:11]1[NH:12][C:13]2[C:18]([C:19]=1[S:20]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:22])=[O:21])=[CH:17][CH:16]=[CH:15][CH:14]=2>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][N:12]2[C:13]3[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:19]([S:20]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)(=[O:21])=[O:22])=[C:11]2[Cl:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 77231-Chloro-4-(chloromethyl)benzeneHCID 13442942HCID 13442942, compound

Product 1

HCID 13800177HCID 13800177, compound

Procedure

This compound was prepared in the same manner as described in Example 17 except that following the addition of 4-chlorobenzylchloride to the anion of 2-chloro-3-phenylsulfonylindole, the reaction mixture was stirred at 90° for 4 hours. The crude product was crystallized from dichloromethane-hexane to give the product.

Workup

  1. customThis compound was prepared in the same manner
  2. customThe crude product was crystallized from dichloromethane-hexane
  3. customto give the product

Sources & evidence

ORD record
ord-b275bd167382440d8f8733643d917164
Source dataset
uspto-grants-1987_03
Patent number
US04654360

Reaction notes

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