HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-(Tetrahydro-pyran-2-yloxy)-cyclobutyl]-methanol → HCID 66779384, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-(Tetrahydro-pyran-2-yloxy)-cyclobutyl]-methanol | HCID 66779483 | — |
| Reactant | (R)-1-(4-fluorophenyl)-6-[6-((R)-3-fluoropyrrolidin-1-yl)-pyridine-3-sulfonyl]-1,4,5,6,7,8-hexahydro-1,2,6-triaza-cyclopenta[b]naphthalene-4a-carbonyl chloride | HCID 86669995 | — |
| Product | HCID 66779384 | HCID 66779384 | — |
Reaction Steps
The title compound was prepared by the method of Preparation 48b using (R)-1-(4-fluorophenyl)-6-[6-((R)-3-fluoropyrrolidin-1-yl)-pyridine-3-sulfonyl]-1,4,5,6,7,8-hexahydro-1,2,6-triaza-cyclopenta[b]naphthalene-4a-carbonyl chloride and [3-(tetrahydro-pyran-2-yloxy)-cyclobutyl]-methanol. LCMS (Method G): 626.6 (M+H)+, Retention time 4.10 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598154B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-75bc91cdee9c4289882b11393314181e |
| Source note | uspto-grants-2013_12 |