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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1907353Generated: November 2, 2026

Hydrochloric Acid → HCID 66624139, compound

https://huagongshe.com/reaction/1907353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 44234055HCID 44234055—
SolventMethanolHCID 887—
SolventIsopropanolHCID 3776—
SolventDichloromethaneHCID 6344—
ProductHCID 66624139HCID 66624139—

Reaction Steps

100 mg of [4-[(2-quinolin-3-yl)imidazo[1,2-a]pyridin-6-yl]thien-2-yl]methanol are suspended in dichloromethane and methanol. The solution is passed through a frit and 5.6 ml of a 0.1N solution of hydrochloric acid in isopropanol are added to the filtrate. The reaction mixture is then concentrated under reduced pressure and the residue is then taken up in diethyl ether. The precipitate is recovered by filtration and oven-dried under reduced pressure. 106 mg of compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598166B2
Source datasetuspto-grants-2013_12
ORD IDord-3499dcdd857b4a04928ce9a20182cd63
Source noteuspto-grants-2013_12