HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Nitrophenyl)piperazine → 1-[(6-Chloro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(4-nitrophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Nitrophenyl)piperazine | HCID 80447 | — |
| Reactant | Ethyl N-(6-chloro-2-methoxyquinoxalin-3-yl)carbamate | HCID 66918182 | — |
| Product | 1-[(6-Chloro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(4-nitrophenyl)piperazine | HCID 66918087 | 82% |
Reaction Steps
Ethyl N-(6-chloro-2-methoxyquinoxalin-3-yl)carbamate and 1-(4-nitrophenyl)piperazine were reacted by the same way with the example 22 to obtain the titled compound (yield, 82%). 1H NMR (300 MHz, DMSO-d6): δ 3.62-3.66 (m, 8H), 4.06 (s, 3H), 7.07 (d, J=9.0 Hz, 2H), 7.58 (d, J=8.4 Hz, 1H), 7.76-7.80 (m, 2H), 8.11 (d, J=9.0 Hz, 2H), 9.46 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598173B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-3dfcb3fce9b34f5a8b8b677ec1edceca |
| Source note | uspto-grants-2013_12 |