3-methoxy-6-methyl-4-nitropyridazine 1-oxide → HCID 21766149, compound

HRID 1907822Notes

Reaction equation

HRID 1907822 reaction equation
[CH3:1][O:2][C:3]1[N:4]=[N+:5]([O-:13])[C:6]([CH3:12])=[CH:7][C:8]=1[N+]([O-])=O.[CH3:14][O-:15].[Na+]>CO>[CH3:1][O:2][C:3]1[N:4]=[N+:5]([O-:13])[C:6]([CH3:12])=[CH:7][C:8]=1[O:15][CH3:14]

Participants

4

Reactant 2

HCID 64053053-methoxy-6-methyl-4-nitropyridazine 1-oxideHCID 10942334Sodium Methoxide

Product 1

HCID 21766149HCID 21766149, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3-Methoxy-6-methyl-4-nitropyridazine 1-oxide (1 g) was converted and worked up analogously to example 1 g). Chromatography of the crude product was unnecessary. The solvent used was methanol (30 ml), and the base sodium methoxide (as 30% solution in methanol, 1.1 ml). Yield: 900 mg LC-MS Rt: 0.29 min [M+H]+:171.1

Sources & evidence

ORD record
ord-73fa67287c55470cb6a518fcc5adc71e
Source dataset
uspto-grants-2013_12
Patent number
US08598177B2

Reaction notes

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