HCID 66998202, compound → HCID 66997025, compound

HRID 1907882Notes

Reaction equation

HRID 1907882 reaction equation
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][N:5]=[C:4]([C:11]([NH:13][C:14]2[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:17]=[CH:16][N:15]=2)=[O:12])[CH:3]=1>CO.C1COCC1.[Pd]>[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][N:5]=[C:4]([C:11]([NH:13][C:14]2[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:17]=[CH:16][N:15]=2)=[O:12])[CH:3]=1

Participants

5

Reactant 1

HCID 66998202HCID 66998202, compound

Product 1

HCID 66997025HCID 66997025, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 83d by hydrogenation of 4-amino-5-nitro-N-(4-trifluoromethyl-pyridin-2-yl)-picolinamide using palladium/charcoal 10% in methanol and THF.

Sources & evidence

ORD record
ord-3c8202d210c4417dbeede35978ebbab4
Source dataset
uspto-grants-2013_12
Patent number
US08598190B2

Reaction notes

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