1,3-Dichloro-2-isothiocyanatobenzene → HCID 86659131, compound

HRID 1907886Notes

Reaction equation

HRID 1907886 reaction equation
[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][N:5]=[C:4]([C:9]([O:11][CH3:12])=[O:10])[CH:3]=1.[Cl:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[C:15]=1[N:21]=[C:22]=[S:23]>C1COCC1.CO>[NH2:8][C:7]1[C:2]([NH:1][C:22]([NH:21][C:15]2[C:16]([Cl:20])=[CH:17][CH:18]=[CH:19][C:14]=2[Cl:13])=[S:23])=[CH:3][C:4]([C:9]([O:11][CH3:12])=[O:10])=[N:5][CH:6]=1

Participants

5

Reactant 2

HCID 1232391,3-Dichloro-2-isothiocyanatobenzeneHCID 66997018Methyl 4,5-diaminopyridine-2-carboxylate

Product 1

HCID 86659131HCID 86659131, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 360f from methyl 4,5-diamino-picolinate and 1,3-dichloro-2-isothiocyanato-benzene in THF and methanol.

Sources & evidence

ORD record
ord-939de792cd3c47598280481bb5090267
Source dataset
uspto-grants-2013_12
Patent number
US08598190B2

Reaction notes

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