Chlorobenzene → HCID 15366480, compound

HRID 1907898Notes

Reaction equation

HRID 1907898 reaction equation
[C:1]1(=[O:12])[O:7][C:5](=[O:6])[C:4]2=[CH:8][CH:9]=[CH:10][CH:11]=[C:3]2[CH2:2]1.[Cl:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([C:1](=[O:12])[CH2:2][C:3]2[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=2[C:5]([OH:7])=[O:6])=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 7964ChlorobenzeneHCID 12801Homophthalic anhydride

Product 1

HCID 15366480HCID 15366480, compound

Procedure

2-[2-(4-Chlorophenyl)-2-oxoethyl]-benzoic acid (above) was prepared by method I using homophthalic anhydride and chlorobenzene. In this case, it was found to be advantageous to heat the reaction to 85° C. for 4 hours. The product was isolated by flash chromatography.

Workup

  1. temperatureto heat
  2. customthe reaction to 85° C. for 4 hours
  3. customThe product was isolated by flash chromatography

Sources & evidence

ORD record
ord-b1e6797c1f554ad7b381c25036c973a4
Source dataset
uspto-grants-2013_12
Patent number
US08598194B2

Reaction notes

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