HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Pyridin-2-yl)propan-1-amine → 2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)-N-(3-hydroxy-4-oxo-1-phenyl-4-(3-(pyridin-2-yl)propylamino)butan-2-yl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Pyridin-2-yl)propan-1-amine | HCID 3159614 | — |
| Reactant | 3-(2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)nicotinamido)-2-hydroxy-4-phenylbutanoic acid | HCID 67239352 | — |
| Product | 2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)-N-(3-hydroxy-4-oxo-1-phenyl-4-(3-(pyridin-2-yl)propylamino)butan-2-yl)nicotinamide | HCID 67239669 | — |
Reaction Steps
The reaction was carried out in analogy to reaction step 1.3 by reacting 3-(2-(3-(4-fluorophenyl)-1H-pyrazol-1-yl)nicotinamido)-2-hydroxy-4-phenylbutanoic acid with 3-(pyridin-2-yl)propylamine; ESI-MS [M+H]+: 579.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598211B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-0fd5235f5692418dac54988ed533bccd |
| Source note | uspto-grants-2013_12 |