HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acid → Ethyl 3-((R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acid | HCID 42127382 | — |
| Reactant | HCID 86644788 | HCID 86644788 | — |
| Product | Ethyl 3-((R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoate | HCID 67095178 | — |
Reaction Steps
The reaction was carried out in analogy to reaction of step 1.1 by reacting (R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acid and 4-ethoxy-3-hydroxy-4-oxo-1-phenylbutan-2-aminium chloride. ESI-MS [M+H]+=443.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598211B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-24cfa6335adf4e2784ccdc069d9cfd64 |
| Source note | uspto-grants-2013_12 |