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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1908705Generated: October 27, 2026

Water → DL-3-n-Butylphthalide

https://huagongshe.com/reaction/1908705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDizocilpineHCID 180081—
ReactantSodium chloride; waterHCID 57417360—
ReactantHCID 153982335HCID 153982335—
ProductDL-3-n-ButylphthalideHCID 61361—

Reaction Steps

l-, d-, and dl-NBP were all provided by department of synthetic pharmaceutical chemistry of our institute, both optical and chemical purity of which are >99%, and the optical activity of which is −66.49°, +66.88° and 0°, respectively. They were formulated with vegetable oil. MK801 is the product of Sigma, and was formulated with physiological brine. Triphenyltetrazolium chloride (TTC), which was manufactured by Beijing Chemical Plant, was formulated with distilled water into 4% solution for use.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598225B2
Source datasetuspto-grants-2013_12
ORD IDord-ef7c642962334a5599037f1bc5a16e14
Source noteuspto-grants-2013_12