HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Isopropylamino-5-methyl-nicotinic acid isopropyl ester → 6-(Isopropylamino)-5-methylnicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Isopropylamino-5-methyl-nicotinic acid isopropyl ester | HCID 67026901 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 6-(Isopropylamino)-5-methylnicotinic acid | HCID 58418084 | 118.1% |
Reaction Steps
A solution of 6-isopropylamino-5-methyl-nicotinic acid isopropyl ester (137 mg, 0.58 mmol) in 25% aq. HCl (5 mL) is stirred at 65° C. for 24 h before it is concentrated and dried to give the title compound (133 mg) as a yellow solid; LC-MS: tR=0.57 min, [M+1]+=195.54.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598208B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-920dc38bc9f043c7a445c051de7d7f6c |
| Source note | uspto-grants-2013_12 |