HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-ethyl-2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-5,6,7,8-tetrahydro-4H-5,8-epoxycyclohepta[b]thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 4-(2-Fluoro-6-trifluoromethyl-benzoylamino)-11-oxa-3-thia-tricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxylic acid | HCID 66845906 | — |
| Product | N-ethyl-2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-5,6,7,8-tetrahydro-4H-5,8-epoxycyclohepta[b]thiophene-3-carboxamide | HCID 25002740 | — |
Reaction Steps
The title compound was prepared from the product of Example 4A and ethylamine according to the procedure described for Example 4B. MS (DCI/NH3) m/z 443 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598224B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-46efbadbfc96474d97ac1f3f76510a98 |
| Source note | uspto-grants-2013_12 |