huagongshe.com
HRID1909017

反应详情

EQUATION

反应方程式

HRID 1909017 的结构方程式

REACTANTS

反应物

2
结构：OCc1ccc(B(O)O)cc1
HCID2734706

4-(Hydroxymethyl)phenylboronic acid

C7H9BO3

结构：CON(C)C(=O)c1ccnc(Br)c1
HCID44818654

未命名化合物

PRODUCTS

生成物

1
结构：CON(C)C(=O)c1ccnc(-c2ccc(CO)cc2)c1
HCID86664344

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.[Pd].[Pd]
催化剂HCID9811564

Bis(dibenzylideneacetone)palladium

C51H42O3Pd2

PROCEDURE

实验过程

By following procedures described in Example 32, starting from 2-bromo-N-methoxy-N-methyl-isonicotinamide and 4-hydroxymethyl phenyl boronic acid [but using Pd2(dba)3 instead of Pd(PtBu3)2], step 1 gave 2-(4-hydroxymethyl-phenyl)-N-methoxy-N-methyl-isonicotinamide.