反应详情

Using 4-bromo-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester (synthesized based on US 2005/0090529 A1, p82) (1 mol. eq.) and 4-cyano-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoic acid methyl ester (2.0 mol. eq.) a starting materials, the reaction was performed using General procedure L (Suzuki) to give 4-(2-cyano-5-methoxycarbonyl-phenyl)-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester. MS(ESI) m/z 378.4 (M+H)+.