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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1909405Generated: October 30, 2026

1-(Trifluoromethyl)cyclopropane-1-carboxylic acid → HCID 178523621, compound

https://huagongshe.com/reaction/1909405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Trifluoromethyl)cyclopropane-1-carboxylic acidHCID 2778306—
ReactantHCID 178479251HCID 178479251—
ProductHCID 178523621HCID 178523621—

Reaction Steps

The title compound, white solid (10 mg, 31.5%), MS (ISP) m/z=467.2 [(M+H)+], was prepared in accordance with the general method of example 1 from Trans-4-[2-(4-Benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexylamine hydrochloride (intermediate A) (25 mg, 0.0681 mmol) and 1-(trifluoromethyl)cyclopropanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08598357B2
Source datasetuspto-grants-2013_12
ORD IDord-f86443ff73744f83a654a548b9f48f50
Source noteuspto-grants-2013_12