HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-(2-Hydroxypropan-2-yl)-3,4'-bipyridine-2'-carboxylic acid hydrochloride salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Isopropyl 6-(2-hydroxypropan-2-yl)-3,4'-bipyridine-2'-carboxylate | HCID 66848234 | — |
| Product | 6-(2-Hydroxypropan-2-yl)-3,4'-bipyridine-2'-carboxylic acid hydrochloride salt | HCID 66848238 | 87% |
Reaction Steps
A solution of isopropyl 6-(2-hydroxypropan-2-yl)-3,4′-bipyridine-2′-carboxylate (140 mg, 0.47 mmol) in 1 M hydrochloric acid (2 mL) was heated at 100° C. overnight. The solvent was removed under reduced pressure to give 6-(2-hydroxypropan-2-yl)-3,4′-bipyridine-2′-carboxylic acid hydrochloride salt as a white powder (106 mg, 87%). 259.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598360B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-97977b2b59ee4a82b6e4ed0c9a978296 |
| Source note | uspto-grants-2013_12 |