HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 86643715, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | HCID 58566560 | HCID 58566560 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 86643715 | HCID 86643715 | — |
Reaction Steps
7-(chloromethyl)-5-fluoro-2,2-dimethyl-2,3-dihydrobenzofuran (647) (1 g, 4.66 mmol), triphenyl phosphine (1.22 g, 4.66 mmol) and toluene (46 mL) were heated at reflux for 48 hours. The reaction was filtered and the solid was washed with diethyl ether to provide ((5-fluoro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)methyl)triphenyl phosphonium chloride (648).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598374B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-1aab53c4d1614b568ae23fa3d5a48c2d |
| Source note | uspto-grants-2013_12 |