Boron tribromide → 4-(4-Methylphenoxy)phenol

HRID 1909624Notes

Reaction equation

HRID 1909624 reaction equation
B(Br)(Br)Br.C[O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)=[CH:9][CH:8]=1>ClCCl>[C:17]1([CH3:20])[CH:16]=[CH:15][C:14]([O:13][C:10]2[CH:11]=[CH:12][C:7]([OH:6])=[CH:8][CH:9]=2)=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 6118401-Methoxy-4-(4-methylphenoxy)benzene

Product 1

HCID 6414404-(4-Methylphenoxy)phenol

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following the general procedure for Example 12 (step 2), boron tribromide (1.0 M solution in dichloromethane, 7.75 mL, 7.75 mmol) was added to the product from step 1 (0.75 g, 3.50 mmol) in dichloromethane (10 mL) to afford the title compound was obtained (0.26 g, 36%) as a yellow solid.

Sources & evidence

ORD record
ord-b69475b9633945b99bb8776fd5020009
Source dataset
uspto-grants-2013_12
Patent number
US08598359B2

Reaction notes

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