HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 4-(Pyridin-4-yloxy)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 68996846 | HCID 68996846 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(Pyridin-4-yloxy)phenol | HCID 18794474 | 95% |
Reaction Steps
The same procedure from Example 143, step 2 was followed using the product from step 1 (306 mg, 0.905 mmol), THF (3 ml), EtOH (9 ml), 10% Pd/C (300 mg, 0.0905 mmol) to give the title compound (160 mg, 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08598359B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-9ccf9612ac404c6f9d99d1fc5a3a5917 |
| Source note | uspto-grants-2013_12 |