Benzyl Bromide → HCID 68998767, compound

HRID 1909815Notes

Reaction equation

HRID 1909815 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:13][C:12]([CH:14]=[O:15])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.C(Br)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:13][C:12]([CH:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[OH:15])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 27978005-(4-methoxyphenyl)thiophene-2-carbaldehyde

Product 1

HCID 68998767HCID 68998767, compoundYield 64%

Procedure

The title compound was prepared from the product of step 1 (0.56 g, 2.55 mmol) and benzyl bromide (0.5 g, 3.2 mmol) using the procedure of Example 159, step 2 with 64% yield (0.6 g).

Sources & evidence

ORD record
ord-9cb9386348304161a05d52cec56c0577
Source dataset
uspto-grants-2013_12
Patent number
US08598359B2

Reaction notes

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