HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 2-(3-Bromophenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | (2-Bromophenyl)boronic acid | HCID 2773294 | — |
| Product | 2-(3-Bromophenyl)pyridine | HCID 11115506 | — |
Reaction Steps
2-bromophenylboronic acid (35.0 g, 0.174 mol) was reacted with 2-bromopyridine (55.1 g, 0.348 mol) under standard Suzuki coupling condition. The excess 2-bromopyridine was removed via vacuum distillation at 125° C. The product was collected at 180° C. as a light yellow liquid (29 g, 71%) and used for the next reaction without additional purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08603645B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-6ce7ed5acda24115b064c90767934736 |
| Source note | uspto-grants-2013_12 |