Hydrochloric Acid → HCID 68536828, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-(2-methoxyethyl)-4-(methoxymethyl)piperidine-1-carboxylate (400 mg) in EtOAc (7 ml) was added 1 N HCl (7 ml) under ice bath cooling, and the mixture was stirred at ambient temperature for 3 hours. The reaction mixture was concentrated in vacuo to give 4-(2-methoxyethyl)-4-(methoxymethyl)piperidine hydrochloride (260 mg) as a white powder. The obtained crude product was used in next reaction without further purification.

Provenance & Evidence