HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 3-aminopyrrolidine-1-carboxylate → Benzyl 3-{[2-(1-oxido-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-6-methylthienopyrimidin-4-yl]amino}-pyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 3-aminopyrrolidine-1-carboxylate | HCID 2756614 | — |
| Reactant | 2-(1-oxido-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-6-methylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 136359788 | — |
| Product | Benzyl 3-{[2-(1-oxido-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-6-methylthienopyrimidin-4-yl]amino}-pyrrolidine-1-carboxylate | HCID 86680739 | — |
Reaction Steps
The title compound was prepared in analogy to Example 3-1 in Scheme 3 by using 2-(1-oxido-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-6-methylthieno[3,2-d]pyrimidin-4(3H)-one and benzyl-3-amino-1-pyrrolidinecarboxylate. MS obsd. (ESI+) [(M+H)+] 548.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604019B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-fa6c31ccc341467f823464af6a57d437 |
| Source note | uspto-grants-2013_12 |