HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1-propanol → HCID 8626742, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Reactant | Benzene, 1-isothiocyanato-4-nitro- | HCID 75044 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 8626742 | HCID 8626742 | 66.2% |
Reaction Steps
A solution of 4-nitro-phenyl-isothiocyanate (4 g, 22.2 mmol) and 2-amino-2-methyl-propan-1-ol (1.9 g, 21.3 mmol) in THF was stirred overnight at r.t. The solvent was evaporated to give a residue which was triturated with ether to give 1-(2-hydroxy-1,1-dimethyl-ethyl)-3-(4-nitro-phenyl)-thiourea (3.8 g, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08604029B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-28cffd716a724f7680cf3e7ca6ce0b80 |
| Source note | uspto-grants-2013_12 |