4-Bromoaniline → N-(4-bromophenyl)-2-(1,1,1-trifluoro-2-methylpropan-2-yl)-5,6,7,8-tetrahydroquinoline-6-carboxamide
Reaction equation
[Br:21][c:22]1[cH:23][cH:24][c:25]([NH2:26])[cH:27][cH:28]1.[CH2:29]([P:30]([OH:31])(=[O:32])[OH:33])[CH2:34][CH3:35].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[F:1][C:2]([C:3]([CH3:4])([CH3:5])[c:6]1[n:7][c:8]2[c:13]([cH:14][cH:15]1)[CH2:12][CH:11]([C:16](=[O:17])[OH:18])[CH2:10][CH2:9]2)([F:19])[F:20].[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1>>[F:1][C:2]([C:3]([CH3:4])([CH3:5])[c:6]1[n:7][c:8]2[c:13]([cH:14][cH:15]1)[CH2:12][CH:11]([C:16](=[O:18])[NH:26][c:25]1[cH:24][cH:23][c:22]([Br:21])[cH:28][cH:27]1)[CH2:10][CH2:9]2)([F:19])[F:20]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-be28da465f684a24ae1ba762e33d6a91
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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