4-(Methylthio)benzaldehyde → HCID 44594373, compound

HRID 1911896Notes

Reaction equation

HRID 1911896 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][C@H:3]([NH:7][C:8]2[CH:9]=[C:10]3[C:14](=[CH:15][CH:16]=2)[NH:13][N:12]=[CH:11]3)[CH2:2]1.[CH3:17][S:18][C:19]1[CH:26]=[CH:25][C:22]([CH:23]=O)=[CH:21][CH:20]=1>C1COCC1>[CH3:17][S:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23][N:1]2[CH2:6][CH2:5][CH2:4][C@H:3]([NH:7][C:8]3[CH:9]=[C:10]4[C:14](=[CH:15][CH:16]=3)[NH:13][N:12]=[CH:11]4)[CH2:2]2)=[CH:21][CH:20]=1

Participants

4

Reactant 2

HCID 769854-(Methylthio)benzaldehydeHCID 66760166HCID 66760166, compound

Product 1

HCID 44594373HCID 44594373, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Reaction of (S)—N-(piperidin-3-yl)-1H-indazol-5-amine and 4-(methylthio)-benzaldehyde using the method of Example 8 and using THF as the reaction solvent afforded the title compound.

Sources & evidence

ORD record
ord-5e010f3dd49d47869bc4e01ded8b262a
Source dataset
uspto-grants-2013_12
Patent number
US08604205B2

Reaction notes

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