4-Aminopyridine → HCID 59799783, compound

HRID 1912010Notes

Reaction equation

HRID 1912010 reaction equation
O=[C:2]1[CH2:7][CH2:6][CH2:5][N:4](C(OC(C)(C)C)=O)[CH2:3]1.[NH2:15][C:16]1[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=1>>[NH:4]1[CH2:5][CH2:6][CH2:7][CH:2]([NH:15][C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 17274-AminopyridineHCID 2756825Tert-butyl 3-oxopiperidine-1-carboxylate

Product 1

HCID 59799783HCID 59799783, compound

Procedure

Reaction of tert-butyl 3-oxopiperidine-1-carboxylate and 4-aminopyridine using the method of Example 3 followed by deprotection using the method of Example 4 affords the title compound.

Sources & evidence

ORD record
ord-a5055785a825471ba90d7f840f0369cd
Source dataset
uspto-grants-2013_12
Patent number
US08604218B2

Reaction notes

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