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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912232Generated: October 26, 2026

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-methionine → HCID 131731085, compound

https://huagongshe.com/reaction/1912232

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-methionineHCID 2724632—
ReactantAsparagine Valine diaminoethane propionyl-maleimideHCID 131731084—
ProductHCID 131731085HCID 131731085—

Reaction Steps

AF-Methionine-(D)Aspartic Acid-diaminoethane-propionyl maleimide (7d) was prepared using the same method as 5c starting with 100 mg of Fmoc-(D)Asp(OtBu)-diaminoethane-trityl resin (3), and using Fmoc-Met as AA1. Yield: 19.4 mg (25%) of white solid. RP-HPLC analysis: >95% at 10.97 min; ESMS m/z=1185.195 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609105B2
Source datasetuspto-grants-2013_12
ORD IDord-dc6b3540b930492cbc76eb7db5ebbc36
Source noteuspto-grants-2013_12