Allyl bromide → N,N-diethyl-4-[(3-methoxyphenyl)-(10-prop-2-enyl-9,10-diazatricyclo[4.2.1.12,5]decan-9-yl)methyl]benzamide

Participants

Reaction Steps

A mixture formed of the compound obtained in example 5.1 (0.98 mmoles), of allyl bromide (1.5 equivalents) and of anhydrous potassium carbonate (3 equivalents) in acetone (25 ml) is heated at reflux for 14 hours. At the end it is filtered and the filtrate is evaporated under vacuum. The compound 4-[(10-allyl-9,10-diazatricyclo[4.2.1.12,5]dec-9-yl)-(3-methoxyphenyl)methyl]-N,N-diethyl benzamide (light solid) is obtained.

Provenance & Evidence