HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58293287, compound → HCID 58293366, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58293287 | HCID 58293287 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 58293366 | HCID 58293366 | 76.5% |
Reaction Steps
A solution of 2-(3-benzylaminopropyl)pyrrolidine-2-carboxylic acid methyl ester (133 mg) in xylene (1.5 ml) was stirred at 130° C. overnight. The mixture was cooled to room temperature, and purified by silica gel column chromatography (eluent: chloroform/methanol=10/1) to give the titled compound (90 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609647B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-8651ee871806468abf7db995e68525b6 |
| Source note | uspto-grants-2013_12 |