HRID1912655

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID443297

未命名化合物

结构：C[C@]12CC[C@H](OC(=O)CCN)CC1C(=O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12.O=C(O)/C=C/C(=O)O

HCID69134025

未命名化合物

PRODUCTS

生成物

结构：C[C@]12CC[C@H](OC(=O)CCN)CC1/C(=N/O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12.Cl

HCID87709700

未命名化合物

PROCEDURE

实验过程

Following the procedure described in Example 1 and starting from 3β-(3-aminopropionyloxy)androstane-6,17-dione fumarate (Prepn. 69, 260 mg) and hydroxylamine hydrochloride (41 mg), the title compound I-dm was obtained (168 mg, 75%), after purification by flash chromatography (SiO2; CH2Cl2:MeOH 9:1). 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 10.42 (1H, s), 8.13 (3H, bb), 4.63 (1H, m), 3.27 (1H, m), 2.98 (2H, t), 2.64 (2H, t), 2.45-0.95 (19H, m), 0.77 (3H, s), 0.69 (3H, s).