HRID1912675

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=C1C[C@@H]2[C@H](CC[C@@]3(C)[C@H]2CC24OCCOC23OCCO4)[C@@]2(C)CCCCC12

HCID67535939

未命名化合物

结构：C[C@]12CCCCC1[C@@H](C=O)C[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC13OCCOC12OCCO3

HCID86635567

未命名化合物

PRODUCTS

生成物

结构：C=C[C@H]1C[C@@H]2[C@H](CC[C@@]3(C)[C@H]2CC24OCCOC23OCCO4)[C@@]2(C)CCCCC12

HCID86635574

未命名化合物

收率 70%

PROCEDURE

实验过程

17,17-Bis(ethylendioxy)-6α-vinylandrostane was prepared in 70% yield from 3,3:17,17-bis(ethylendioxy)-6α-formylandrostane by the procedure described above for the preparation of 3,3:17,17-bis(ethylendioxy)-6-methyleneandrostane (Prepn. 8). The crude was purified by flash chromatography (SiO2, n-hexane/EtOAc 88/12). 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 5.47 (m, 1H), 4.91 (m, 2H), 3.94-3.73 (m, 8H), 2.00-0.67 (m, 21H), 0.88 (s, 3H), 0.83 (s, 3H),

WORKUP

后处理

customThe crude was purified by flash chromatography (SiO2, n-hexane/EtOAc 88/12)