HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69133284, compound → (7E,8R,9S,10S,13S,14S)-7-methoxyimino-10,13-dimethyl-1,2,4,5,6,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69133284 | HCID 69133284 | — |
| Reactant | HCID 178502611 | HCID 178502611 | — |
| Product | (7E,8R,9S,10S,13S,14S)-7-methoxyimino-10,13-dimethyl-1,2,4,5,6,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione | HCID 87654088 | 55% |
Reaction Steps
The title compound II-br was prepared in 55% yield from 3,3:17,17-bis(ethylendioxy)-7(E)-methoxyiminoandrostane by the procedure described above for the preparation of 6α-cyanoandrostane-3,17-dione (II-ac, Prepn. 3). The crude product was purified by flash chromatography (SiO2, n-hexane/EtOAc 6/4). 1H-NMR (300 MHz, DMSO-d6, ppm from TMS: δ 3.72 (s, 3H), 2.89 (m, 1H), 2.63-0.93 (m, 19H), 1.12 (s, 3H), 0.82 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609644B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-be8d67332cf54185a393d45640e769ee |
| Source note | uspto-grants-2013_12 |