HCID 69133284, compound → 7alpha-Formamidoandrostane-3,17-dione

Participants

Reaction Steps

The title compound II-bu was prepared in 97% yield from 3,3:17,17-bis(ethylendioxy)-7α-formamidoandrostane by the procedure described above for the preparation of 6α-cyanoandrostane-3,17-dione (II-ac, Prepn. 3). The crude product was purified by flash chromatography (SiO2, n-hexane/acetone 70/30). 1H-NMR (300 MHz, DMSO-d6, ppm from TMS: δ 8.18 (dd, 1H), 7.97 (d, 1H), 4.13 (m, 1H), 2.90-0.95 (m, 20H), 1.00 (s, 3H), 0.79 (s, 3H).

Provenance & Evidence