Methylamine → HCID 23155096, compound

HRID 1912783Notes

Reaction equation

HRID 1912783 reaction equation
[Cl:1][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][CH:5]=[N:6]2.[CH3:11][NH2:12].F[C:14]1[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=1.[Cl:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]=[C:31]=[O:32])=[CH:26][C:25]=1[C:33]([F:36])([F:35])[F:34]>>[ClH:1].[Cl:23][C:24]1[CH:29]=[CH:28][C:27]([NH:30][C:31]([NH:20][C:17]2[CH:18]=[CH:19][C:14]([N:6]3[CH:5]=[N:4][C:3]4[C:7]3=[N:8][CH:9]=[N:10][C:2]=4[NH:12][CH3:11])=[CH:15][CH:16]=2)=[O:32])=[CH:26][C:25]=1[C:33]([F:34])([F:35])[F:36]

Participants

5

Reactant 4

HCID 6329MethylamineHCID 9590p-FluoronitrobenzeneHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 53592776-Chloropurine

Product 1

HCID 23155096HCID 23155096, compound

Procedure

The title compound can be synthesized from 6-chloropurine, methylamine, 4-fluoronitrobenzene and 4-chloro-3-(trifluoromethyl)phenyl isocyanate by the same method as in Example 35.

Sources & evidence

ORD record
ord-08dd2ff7673b4554a0f3b0811f27a7c8
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

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