Purine → HCID 23155107, compound

HRID 1912790Notes

Reaction equation

HRID 1912790 reaction equation
[N:1]1[CH:9]=[C:8]2[C:4]([N:5]=[CH:6][NH:7]2)=[N:3][CH:2]=1.F[C:11]1[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=O)=[CH:13][CH:12]=1.[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([N:27]=[C:28]=[O:29])=[CH:23][C:22]=1[C:30]([F:33])([F:32])[F:31]>>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([NH:27][C:28]([N:17]([OH:19])[C:14]2[CH:13]=[CH:12][C:11]([N:5]3[CH:6]=[N:7][C:8]4[C:4]3=[N:3][CH:2]=[N:1][CH:9]=4)=[CH:16][CH:15]=2)=[O:29])=[CH:23][C:22]=1[C:30]([F:31])([F:32])[F:33]

Participants

4

Reactant 3

HCID 1044PurineHCID 9590p-FluoronitrobenzeneHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzene

Product 1

HCID 23155107HCID 23155107, compound

Procedure

The title compound can be synthesized from purine, 4-fluoronitrobenzene and 4-chloro-3-(trifluoromethyl)phenyl isocyanate by using the same techniques as in Example 45.

Sources & evidence

ORD record
ord-d8b028013caf47c392bf69ba15f1b5bc
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

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