Methylamine → HCID 11248817, compound

HRID 1912810Notes

Reaction equation

HRID 1912810 reaction equation
CO[C:3]([C:5]1[C:10]2[N:11]=[CH:12][N:13]([C:14]3[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=3)[C:9]=2[CH:8]=[CH:7][N:6]=1)=[O:4].[CH3:23][NH2:24].[Cl:25][C:26]1[CH:31]=[CH:30][C:29]([N:32]=[C:33]=[O:34])=[CH:28][C:27]=1[C:35]([F:38])([F:37])[F:36]>>[CH3:23][NH:24][C:3]([C:5]1[C:10]2[N:11]=[CH:12][N:13]([C:14]3[CH:15]=[CH:16][C:17]([NH:20][C:33]([NH:32][C:29]4[CH:30]=[CH:31][C:26]([Cl:25])=[C:27]([C:35]([F:36])([F:37])[F:38])[CH:28]=4)=[O:34])=[CH:18][CH:19]=3)[C:9]=2[CH:8]=[CH:7][N:6]=1)=[O:4]

Participants

4

Reactant 3

HCID 6329MethylamineHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 59725913HCID 59725913, compound

Product 1

HCID 11248817HCID 11248817, compound

Procedure

The title compound can be synthesized from 1-(4-nitrophenyl)-1H-imidazo[4,5-c]pyridine-4-carboxylic acid methyl ester, methylamine and 4-chloro-3-(trifluoromethyl)phenyl isocyanate in the same manner as in Steps C and D of Example 92.

Sources & evidence

ORD record
ord-2248c70e51134d008d91617b3fe7ca39
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

Loading…