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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912818Generated: November 1, 2026

(2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acid → HCID 178448325, compound

https://huagongshe.com/reaction/1912818

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acidHCID 637605—
Reactant1-[4-(6-Aminopurin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochlorideHCID 23155120—
ProductHCID 178448325HCID 178448325—

Reaction Steps

The titled compound can be synthesized from 1-[4-(6-amino-purin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochloride and tert-butoxycarbonyl-D-valine by using the same method as in Example 96.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609656B2
Source datasetuspto-grants-2013_12
ORD IDord-b9071a86e64a4f0b91906a8b5df286c6
Source noteuspto-grants-2013_12