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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912822Generated: November 1, 2026

(2S)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoic acid → HCID 86620273, compound

https://huagongshe.com/reaction/1912822

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoic acidHCID 7010555—
Reactant1-[4-(6-Aminopurin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochlorideHCID 23155120—
ProductHCID 86620273HCID 86620273—

Reaction Steps

The title compound can be synthesized from 1-[4-(6-aminopurin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochloride and N-methyl-tert-butoxycarbonyl-L-leucine by using the same method as in Example 96.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609656B2
Source datasetuspto-grants-2013_12
ORD IDord-37df33dee1794575ba303e6c22a46e0b
Source noteuspto-grants-2013_12