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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912873Generated: October 25, 2026

Dimethylamine → 1-(4-Dimethylaminomethyl-3-(trifluoromethyl)phenyl)-3-[4-(6-(methylamino)purin-9-yl)phenyl]urea

https://huagongshe.com/reaction/1912873

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant(9-{4-[3-(4-formyl-3-(trifluoromethyl)phenyl)ureido]phenyl}-9H-purin-6-yl)-methylcarbamic acid tert-butyl esterHCID 59725906—
Product1-(4-Dimethylaminomethyl-3-(trifluoromethyl)phenyl)-3-[4-(6-(methylamino)purin-9-yl)phenyl]ureaHCID 23155035—

Reaction Steps

The title compound can be prepared from dimethylamine and (9-{4-[3-(4-formyl-3-(trifluoromethyl)phenyl)-ureido]phenyl}-9H-purin-6-yl)-methyl-carbamic acid tert-butyl ester by using the same techniques as in Example 168.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609656B2
Source datasetuspto-grants-2013_12
ORD IDord-8487ea2b6d2744d2afdb39a33ca2db02
Source noteuspto-grants-2013_12