Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-((1S,2S,5S)-6,6-Dimethylbicyclo[3.1.1]heptan-2-yl)acetic acid | HCID 67161116 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86665150 | HCID 86665150 | — |
Reaction Steps
To a mixture of the product from Example 4B (300 mg, 1.65 mmol) and thionyl chloride (901 μL, 12.4 mmol) was added a drop of dimethylformamide. The reaction was stirred at 22° C. for 2 hours. The excess of thionyl chloride was evaporated and the residue was dried under vacuum to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08609669B2 |
|---|
| Source dataset | uspto-grants-2013_12 |
|---|
| ORD ID | ord-725e7c30827546548599d3f286001c5d |
|---|
| Source note | uspto-grants-2013_12 |
|---|
