Hydrazine hydrate (1:1) → HCID 50741933, compound

HRID 1912896Notes

Reaction equation

HRID 1912896 reaction equation
[F:1][C:2]1[CH:13]=[CH:12][C:5]([CH2:6][CH:7]([C:10]#[N:11])[C:8]#[N:9])=[CH:4][CH:3]=1.O.[NH2:15][NH2:16]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][C:7]2[C:10]([NH2:11])=[N:15][NH:16][C:8]=2[NH2:9])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 12425844HCID 12425844, compound

Product 1

HCID 50741933HCID 50741933, compound

Procedure

The product from Example 5A (1.5 g, 8.61 mmol) and hydrazine monohydrate (2.111 mL, 43.1 mmol) was processed using the method analogous to that described in Example 1B to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 9.96 (s, 1H) 7.15-7.51 (m, 2H) 6.79-7.11 (m, 2H) 4.30 (s, 4H) 3.48 (s, 2H). MS (ESI) m/z 259.3 (M+H)+.

Sources & evidence

ORD record
ord-b6a53eba94a74f18b7a4798f89a6d665
Source dataset
uspto-grants-2013_12
Patent number
US08609669B2

Reaction notes

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